This paper holds a parametric study on seakeeping performance for one kind of submersible vehicles, a tourist submarine. This analyis has been performed from the aspect of motion sickness incidence by using a strip theory hydrodynamics solver. The parameters include sea state, sea direction, depth, speed and duration of operation. Results prove head seas to be more violative than following seas. Moreover, Effect of trip duration, operating depth and vessel forward speed on operability index has been investigated.